Multichannel array detection of vibrational optical activity free-induction-decay

By introducing a multichannel array detector to vibrational optical activity free-induction-decay (VOA FID) measurement spectrometer, we successfully measured the vibrational circular dichroism (VCD) spectrum of (1S)-β-pinene. By virtue of its fast measurement capability without a large number of frequency scans, the data collection time needed to obatain a high-quality VCD spectrum can be substantially reduced down to less than a minute. We anticipate that this type of linear chiroptical spectrometer will be applicable to a variety of vibrational optical activity studies of biomolecules and drugs.