Antibacterial Activity Of Leaves Extracts Of Jatropha Curcas Linn Against Enterobacter Aerogenes

Abstrak This study aims to analyze the antibacterial activity of leaves extract of Jatropha curcas against Enterobacter aerogenes and determine of Minimum Inhibitory Concentration. The extraction process is done by maceration method using hexane chloroform ethyl acetate and methanol. Extracts obtained test antibacterial activity against Enterobacter aerogenes. Concentration all extract of Jatropha curcas is 1 10 20 and 30 w v. Positive control using synthetic antibiotic ampicillin and negative controls used dimethyl sulfoxide DMSO. The results showed that the negative control DMSO and positive control ampicillin do not provide inhibition against test bacteria. Positive controls that do not provide inhibition against test bacteria showed that bacteria tested was resistant to antibiotics ampicillin used. All types of extracts with concentrations of 1 to 30 w v gave inhibition against test bacteria. The highest inhibition diameter found in the chloroform extract with a concentration of 20 14.83 1.66 mm and the lowest was in 1 hexane 653 0.18mm. The diameter of the inhibition of the bacterium Enterobacter aerogenes to all types of extracts tended to increase with increasing concentration of the extract. MIC values for all existing extract at a concentration of 0.75 w v.