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15-Lipoxygenase Inhibitory Activity Of The Extracts From Clerodendrum Quadriloculare Blanco Merr. Lamiaceae Leaves
Journal: International Journal of Scientific & Technology Research (Vol.4, No. 9)Publication Date: 2015-09-15
Authors : Kay Ann J. Tongol; Joseph Mari B. Querequincia;
Page : 269-271
Keywords : Index Terms Clerodendrum quadriloculare; Lamiaceae; 15-Lipoxygenase; Phytosterols; Clerosterol; Philippines;
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Abstract
Abstract Clerodendrum quadriloculare Blanco Merr. is an endemic plant species of the genus Clerodendrum in the Philippines. This plant contains phytosterols which may contribute to its biological properties. Results of this present research work established the anti-inflammatory potential by inhibiting 15-lipoxygenase enzyme in an in vitro assay model. The methanolic extract of C. quadriloculare possessed significant inhibition against 15-lipoxygenase enzymes with an IC50 value of 0.38 mgmL.
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Last modified: 2015-11-13 18:32:49