Estimation And Forced Degradation Study Of Thiazole Derivative By HPLC Technique
Journal: International Journal of Scientific & Technology Research (Vol.4, No. 9)Publication Date: 2015-09-15
Authors : D.B.Kamkhede; P.R.Solanki.;
Page : 393-399
Keywords : KEYWORDS HPLC Method Validation; Force degradation of thiazole derivative;
Abstract
ABSTRACT The development and validation of thiazole derivatives under various stress conditions as acidbase hydrolysis oxidative stress degradations. As carried out in this process.the simultaneous forced degradation study of thiazole derivatives using gradient pump system the mobile phase water methanol 3070 was selected to achieve maximum detection sensitivity at ambient temperature using phenomax c-18 column 250 mm 4.5 mm526956l flow rate 1.0 mlmin at 238 nm.the proposed method was found to be rapid accurate and consistent.
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