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OSTEOPONTIN, INTERLEUKIN-15 AND DYSFUNCTION OF LEFT VENTRICULAR MYOCARDIUM IN HYPERTENSIVE PATIENTS WITH CHRONIC HEART FAILURE

Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.32, No. 32)

Publication Date:

Authors : ; ; ;

Page : 19-23

Keywords : osteopontin; interleukin-15; hypertension; left ventricular myocardial dysfunction; chronic heart failure;

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Abstract

Based on a survey of 108 patients with hypertension complicated by chronic heart failure, studied the connection concentration of osteopontin, interleukin-15 inserum and morpho-functional characteristics of the left ventricle of the heart. In patients with CHF osteopontin levels were significantly higher, it revealed a relationship between adverse LV filling state and knots in serum osteopontin, while the level of IL-15 did not show such a relationship. The results indicate the potential value of osteopontin as a biomarker for the diagnosis of CHF.

Last modified: 2017-01-02 21:06:12