CHARACTERISTIC OF MICROCIRCULATORY ABNORMALITIES IN ADOLESCENTS WITH OSTEOARTHROSIS IN CATAMNESIS

Using nail bed capillaroscopy, there has been examined microcirculation system (MCS) status in 43 adolescents with osteoarthrosis (OA), which formation had been accompanied by hypermobile syndrome (HMS) and old reactive arthritis. MCS examination has been carried in hospital before administration of therapy and one month after; the therapy included nonsteroid anti-inflammatory preparations, administered during 2-3 weeks, and chondroprotectors (Teraflex, 1 capsule 3 times daily). It has been established that MCS abnormalities manifested themselves in vascular, intravascular and perivascular parts. Vascular anatomical abnormalities such as a decrease in quantity of capillaries and their rows; dilatation, sinuousity, irregular disposition, favoured the aggregation of erythrocytes and delayed blood circulation, - the factors of intravascular abnormalities, - and blurred, pale background - the factor of perivascular MCS part abnormality. Such features had been mostly present in a more prolonged pathological process of OA accompanied by HMS. It has been established that medicamental therapy administration caused a decrease in MCS abnormalities frequency. It has been manifested by an increase in the number of functioning capillaries and blood circulation normalization in most cases.