DETERMINANTS OF ACUTE MYOCARDIAL INFARCTION OF WORCESTER HEART ATTACK STUDY

Objectives: This article aims to identify the determinants of the Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP) and the Heart Rate (HR) of the Acute Myocardial Infarction (AMI) patients in the Worcester Heart Attack Study (WHAS). Background: Little is known about the determinants of SBP, DBP and HR of AMI patients in the WHAS. Methods: The responses DBP, SBP and HR are positive with non-constant variances, so joint log-normal or gamma model fittings are appropriate for these responses. Results: Mean DBP is inversely separately associated with age (P < 0.001), congestive heart complications (CHF) (P = 0.007) and Myocardial Infarction (MI) order (MIORD) (P = 0.054), and it is directly separately associated with HR (P < 0.001), SBP(P < 0.001), a trial fibrillation (AFB) (P = 0.072), cardiogenic shock (SHO) (P = 0.036), myocardial infarction (MI) type (MITYPE) (P < 0.001). Mean SBP is negatively separately associated with HR (P < 0.001), AFB (P = 0.011), SHO (P < 0.001), MITYPE (P < 0.001), and it is positively separately associated with age (P = 0.013), sex (P = 0.002), DBP (P < 0.001), history of cardiovascular disease (CVD) (P = 0.011). Mean HR is inversely separately associated with SBP (P < 0.001), history of cardiovascular disease (CVD) (P = 0.095), complete heart block (CV3) (P = 0.033), MITYPE (P < 0.001), cohort year (YEAR) (P = 0.032), and it is positively separately associated with AGE (P = 0.039), DBP (P < 0.001), CHF (P < 0.001). Conclusions: Determinants of mean and variance of SBP, DBP and HR of AMI patients in the WHAS are derived in this report. Effects of these determinants on their responses are also derived. These derived effects are almost new in the WHAS literature.