FEATURES OF PROTEIN STRUCTURE AND THE IMMUNOGENICITY OF ACTUAL INFLUENZA VACCINES

Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.21, No. 21)

Publication Date: 2011-06-30

Authors : A. Yu. Volyanskiy; E. A. Romanova; T. A. Sydorenko; N. I. Igumnova; V. I. Yuchimenko; N. V. Kashpur; A. V. Martynov;

Page : 5-9

Keywords : vaccines against a virus of influenza; immunogenicity; albuminous composition;

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Abstract

Immunogenicity and the basic characteristics of albuminous components of new vaccines against a virus of influenza A (H1N1) by Panenza and MonoGrippol were investigated. The quantitative and qualitative structure of proteins of both vaccines is revealed: five ? the split vaccine of Panenza, two ? subisolated vaccines of MonoGrippol. It was established that the immunogenicity of investigated subisolated adjuvant vaccine twice exceeds an immunogenicity of viral-split nonadjuvant vaccine.

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FEATURES OF PROTEIN STRUCTURE AND THE IMMUNOGENICITY OF ACTUAL INFLUENZA VACCINES

Abstract

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