RELATION BETWEEN PATIENTS WITH GASTRIC HELICOBACTER PYLORI INFECTION AND DYSLIPIDEMIA

Objective: To evaluate the relation between gastric H. pylori infection and dyslipidemia. Methods: Eligible subjects were all adult; we enrolled those patients with dyspepsia who had undergone esophagogastroduodenoscopy. They were divided in 2 groups: Case group: patients who have a histologic diagnosis of infection for H. pylori. Control group: Patients who had previous negative biopsy for H. pylori. All patients had basic serology and lipid profiles, both groups were compared. Results: 120 patients were evaluate, 63 were female (52.5%). Of 77 patients with dyslipidemia, 40 were positive H. pylori (51.9%), and 20 of 43 non ? dyslipidemic patients were positive H. pylori (46.5%). Cholesterol values were 196.6 ± 42.1 and 191.7 ± 29.5; triglyceride 164.4 ± 89.1 and 139.2 ± 69.1; LDL 119.2 ± 33.8 and 115.9 ± 27.4; VLDL 33.1 ± 17.6 and 29.1 ± 15.6, HDL: 44.4 ± 9.1 and 42.5 ± 10.7 for the positive and negative H. pylori groups, respectively. “p” values in all cases were not statistically significant: cholesterol (p = 0.4), triglycerides (p = 0.08), HDL (p = 0.3), LDL (p = 0.5), VLDL (p = 0.1). Conclusions: Gastric H. pylori infection does not have significant relation with the presence of dyslipidemia. The alterations of the serum lipids profiles (cholesterol, triglycerides, LDL and VLDL) are discreetly higher in the patients infected by H. pylori, but they are not statistically significant.