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Journal: Journal of Gastrointestinal Disorders and Liver function (Vol.2, No. 2)

Publication Date:

Authors : ;

Page : 1-4

Keywords : Primary splenic lymphoma; Splenectomy; Chemotherapy;

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Background: Primary splenic lymphoma is a rare disease with heterogeneous definition, compromising less than 1% of non-Hodgkin's lymphoma. Case presentation: We are reporting a case of 50 year old man who presented splenomegaly, fever, weight loss and night sweats. The investigations revealed a splenomegaly with splenic lesion which cancorrespond to abscess. The patient underwent splenectomy for definitive diagnosis and treatment. Diagnosis of primary diffuse large B cell lymphoma of the spleen was made and confirmed by immunochemistry and the patient received 6 cycles of RCHOP (Rituximab + cyclophosphamide + Adriamycin + vincristine + prednisone) and he is currently well and in complete remission more than 1 year after diagnosis. Conclusion: Primary splenic lymphoma is rare; splenectomy is an important step in its diagnosis and treatment. Early splenectomy combined with chemotherapy is an optimal strategy.

Last modified: 2017-01-09 16:25:40