EPIDERMOLYTIC HYPERKERATOSIS: A CASE REPORT FROM YEMEN

Epidermolytic hyperkeratosis is a rare autosomal dominant disorder of cornification with a prevalence of 1:100,000 to 1:300,000, which affect both sexes equally. We report the case of a 10-year-old girl who presented to the dermatology clinic with dirty brown, corrugated hyperkeratotic plaques involving joint flexures and the trunk. She had similar lesions arranged in a cobblestone pattern over the knees, elbows, and dorsal hands and feet, in addition to multiple superficial erosions. She had a history of generalized erythroderma and trauma-related blistering at the time of birth. All other family members were healthy, and had no such skin manifestations.