DISCOVERY OF ADIPONECTIN AND ITS FUTURE PROSPECT

Adiponectin is an adipocyte-specific protein abundantly present in the plasma. Since its discovery, numerous experimental and clinical studies have demonstrated that adiponectin has anti-atherogenic, antidiabetic and anti-inflammatory properties. Hypoadiponectinemia plays a key role in the pathogenesis of metabolic syndrome. In this manuscript, we review the discovery and establishment of adiponectin and discuss future prospects of this molecule.