SERUM URIC ACID AS A PREDICTOR OF PRE-ECLAMPSIA

Aims and objectives To predict preeclampsia using serum uric acid levels in antenatal normotensive patient and to assess the severity of pre-eclampsia using the serum uric acid levels. Study design It is a prospective observational study of 120 patients visiting our institution at 20 weeks of gestation. The cut-off value of serum uric acid was taken as 6 mg. They were followed for the development of signs of pre-eclampsia.Result It was observed that 64 patients had uric acid 6mg percent of which 55 developed pre-eclampsia (86 percent) and about 9 remained normotensives (14 percent). Twenty four (37 Percent) patients with pre-eclampsia developed complications like (15 percent)7 eclampsia, (6 percent) 3 placental abruption , (4 percent)1 HELLP syndrome, one pulmonary edema and 12 with signs of imminent eclampsia.Conclusion In our study patients with uric acid 6mg became preeclamptic and also the serum uric acid levels correlated with the maternal complications of pre-eclampsia.