Autoimmune Thyroid Diseases in Celiac Disease: If and When to Screen?

Prevalence of autoimmune thyroiditis is increased in patients with celiac disease and vice versa. Both diseases are frequent autoimmune diseases sharing multiple aspects lodging at the two ends of the gut-thyroid axis where the cross-talks' pathways are still unrivalled. Many authors recommend screening patients with thyroid autoimmunity for celiac disease associated antibodies. However, routine screening of celiac patients for anti-thyroid antibodies is less clear. Despite the fact that the latter screening fulfills most of the criteria for screening a disease, the timing and cost-effectiveness remains undetermined. For now, in face of celiac disease, the increased prevalence of autoimmune thyroid diseases needs to be taken in account and the accurate diagnosis should not be delayed.