COMPARE CHARACTERISTIC OF CLINICAL STATE AND INDEX OF LIPID SPECTRUM DYNAMICS IN PATIENTS WITHOUT AND AFTER AORTIC-CORONARY BYPASS DURING THE STAGES OF ATORVASTATIN THERAPY
Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.13, No. 13)Publication Date: 2006-12-30
Authors : O.О. Gunaeva-Kruchina;
Page : 83-88
Keywords : chronic ishemic heart disease; atorvastatin; lipid spectrum; clinical state; dislipoproteide-mia;
Abstract
During the investigation 40 out ? patients with chronic ischemic heart disease (CIHD) 18 ? without 22 ? after aortic?coronary bypass (acb) were observed. The average period of time after operation before initial investigation comprised (1?3, 5) years. Patients were divided into 2 groups according to the types of dislipoproteidemia. 10 patients without асb has 2a type of dislipoproteidemia, 8 ? 2b type, 15 patients after aortic?coronary bypass ? 2a type, 7 ? 2b type. Аll patients received atorvastatin 10 mg. Dynamics of clinical state evaluates by patient complaints of dispnea, angina pectoralis and stability of physical loards. Total cholesterol, LDL, VLDL, HDL, triglycerides, index of atherogenity were evaluated ones at 3 months. During the therapy the optimization index of lipid spectrum and clinical state indices was noted in all patients, without regarding aortic coronary bypass and grade of dislipoproteidemia. Durig the investigation after 3 months it came the decrease of lipid level and angina pectoralis attack, increase stability of physical loards.
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