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CLINICAL ASPECTS OF THE LIVER MICROSOMAL CYTOCHROME P-450 SYSTEM FUNCTIONING
Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.11, No. 11)Publication Date: 2005-12-30
Authors : V.I. Padalko; T.V. Sevastyanova;
Page : 105-117
Keywords : сytochrome P-450; multiple forms; drug-drug interactions;
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Abstract
In the present review modern representations about cytochrome P-450 system and roles of its major multiple forms in an organism are generalized. Drugs induction or inhibition of this system are discussed. Important for clinic interactions of drugs with P-450 enzymes are given and practical ways of prevention or minimization of negative consequences of interactions of medical products are discussed.
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Last modified: 2017-01-15 02:27:43