PECULIARITIES OF MICROBIAL INTERACTIONS IN BIOCENOSЕS OF GASTRODUODENAL TRACT

The study aimed to investigate peculiarities of microbial interactions in biocenoses of stomach and duo-denum mucosal membranes at inflammatory-ulcer pathology of gastroduodenal tract. It was determined availability of antagonistic properties in 74 strains of opportunistic microflora (A. viridans, Вacillus spp, Corynebacterium spp, Pseudomonas spp, Staphylococcus spp and others). It was found that, in opposite to monocultures, complex associations of urease positive microorganisms from mucosal membranes bioptates (tissue urea determination) as well as designed microbial associations which included representatives of isolated mucosal microflora showed stimulating effect on the urea decomposition rate. Antibiotic sensitivity of microorganisms in complex microbial associations and in separate associants was shown to be significantly different: the latter showed higher sensitivity to antimicrobial preparations.