LOCAL LIMPHOCYTIC REGULATION OF HEMATOPOETIC TISSUE RECOVERY OF IRRADIATED RECIPIENTS AFTER INJECTION OF THE MYELOTRANSPLANT AT THE LEVEL OF THEIR BONE MARROW
Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.10, No. 10)Publication Date: 2005-06-30
Authors : N.N. Popov; E.A. Romanova; S.B. Lavelin;
Page : 96-99
Keywords : transplantation; bone marrow; lymphocytes; regulation;
Abstract
High supression of proliferation of simulated splenocyts by bone marrow lymphocytes in vitro which appeared on the 30 day of the study was noted after the total irradiation of (CBAxC57BL)F1 mice in the dose 9 Gy and following the syngenic mielo- and lymphomielotransplant injections. More manifested suppressory activity was observed in the lymphocytes of the animals, injected with a combined transplant as compared to the cells of the animals, injected with myelocaryocytes per se. A phenotypic study of the bone marrow cells has shown that the T-depleted fraction lymphocytes, which expressed sIg-molecules and cells, characterised by a phenotype of the zero-lymphocytes, exibits suppressory properties.
Other Latest Articles
- DETERMINATION OF HEALTH LEVEL OF THE FIRST FORM SCHOOLCHILDREN ON FOUNDATION OF COMPLEX ESTIMATION OF ORGANISM’S ADAPTATION POSSIBILITIES
- THE POSSIBILITIES OF CARDIOINTHERVALOGRAPHY IN DIAGNOSTICS AND TREATMENT CONTROL OF VEGETATIVE REGULATION DISTURBANCES IN THE PATIENTS WITH CHRONIC GLOMERULONEPHRITIS
- DISFUNCTION OF ENDOTHELIUM WITH CHRONIC CARDIAC INSUFFICIENCY AND INFLUENCE OF INHIBITORS RENIN-ANGIOTENSIN SYSTEM
- PECULIARITIES OF DEVELOPMENT AND EVOLUTION OF SCLERODERMIC DISEASE IN CHILDREN AND ADOLESCENTS
- THE ANTIBIOTICOSENSITIVITY CHANGE OF DIPHTHERIA AND WHOOPING-COUGH UNDER THE INFLUENCE OF ELECTROMAGNETIC WAVES OF MILLIMETRE RANGE
Last modified: 2017-01-15 04:24:06