TYPE OF REACTION OF SIMPATO-VAGAL BALANCE IN A ACUTE FARM TEST WITH A METOPROLOL AND EFFICIENCY OF THERAPY OF HEART FAILURE

The connection of efficiency of therapy by metoprolol (MT) with type of reactions of neurogumoral regulation on this drug in acute farm test (AFT) was investigated in 106 patients with a chronic heart failure. The type of reaction was determined by a heart rate variability method by change of sympathovagal balance (SVB) in AFT. Clinic and haemodinamic parameters and parameters of ultrasonic scanning of heart were studied prior to the beginning and upon termination of a stage of therapy by MT. By more significant the outcomes of therapy have appeared among the patients with decreasing of SVB.