THE INDEXES OF CELL IMMUNITY AMONG PATIENTS WITH CHRONIC HEPATITIS C DUE TO THE LEVEL OF ALANIN-AMINE-TRANSPHERAZE PLASMA

The total number of lymphocytes and expression of superficial antigens CD3, CD4, CD8, CD20, CD56 were studied in the lymphocytes of peripheral blood among 40 patients with chronic HCH. The first group consists of 16 patients with normal level of AlAT, the second one-24 patients with high level of AlAT. Discovered the true (p<0,05) decrease of OCHL, percent cell, expressing antigens CD3+, CD56+ and index CD4/CD8 among the patients of the first group and the true (p<0,05) decreasing OCHL percent cells CD3+, CD4+, CD8+ and CD56+, increasing CD20+ among patients of the second group compare to control. The comparing of immune indexes in patients in group 1 and 2 turned out the true (p<0,05) difference in the type of decreasing OCHL, expression of antigen CD3+ and increasing of the percent of cells, expressing antigens CD4+ and CD8+ among patients with normal level of AlAT.