THE METABOLIC ACTIVITY OF MEDULLAR CELLS AT STAGES OF HAEMOPOESIS RECOVERING OF THE ANIMALS AFTER IRRADIATIATION AND MYELOTRANSPLANTATION
Journal: The Journal of V.N. Karazin Kharkiv National University, series "Medicine" (Vol.2, No. 2)Publication Date: 2001-12-30
Authors : E.A. Romanova;
Page : 108-112
Keywords : metabolism; marrow; transplantation;
Abstract
The intensity of myelocariocytes metabolism from the tenth day after lethal irradiation of mice till the nineti-eth and transplantation of medullar cells was studied. The activity of energetic metabolic enzymes and the state of the lipid peroxidation ? antioxidation protection system of myelocaryocytes was investigated. It was shown that a significant activity increase of myelocaryocytes enzymes took place at the stage of medullar cells recovery. At the same time the activation of lipid peroxidation processes is accompanied by an increase of antioxidant resources enabling effective control of free-radical oxidation in medullar cells.
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