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The role of intra abdominal hypertension and maternal venous compartment in the pathophysiology of pre-eclampsia

Journal: The Greek E-Journal of Perioperative Medicine (Vol.12, No. 1)

Publication Date:

Authors : ; ; ; ;

Page : 28-38

Keywords : intra-abdominal hypertension; maternal venous compartment; preeclampsia; rennin-angiotensin-anldosterin system;

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The incidence of preeclampsia in the western countries is estimated to range from 2% to 6% in healthy, nulliparous women. In developing nations, the incidence of the disease is reported to be 4- 18%,with hypertensive disorders being the second most common obstetric cause of stillbirths and early neonatal deaths in these countries Etiology of the disease is multifactorial, with risk factors like ma-ternal age, oxidative stress, angiotensin T-235 homozygote having a different role in every case. Moreover, the disease its self is a multisystem expression of a complicated pathophysiology. Many attempts to explain the latter have been made with often controversial results. In the present article we explore the hypothesis of intra-abdominal pressure as possible causative factor of preeclampsia and the role ofthe maternal venous compartment and rennin-angiotensin-anldosterin system in this hypothesis.

Last modified: 2017-01-20 20:08:58