THE STRUCTURAL AND FUNCTIONAL STATE OF THE C-CELLS OF THE THYROID GLAND IN HYPOPHYSECTOMIZED ANIMALSJournal: I.P. Pavlov Russian Medical Biological Herald (Vol.24, No. 3)
Publication Date: 2016-09-28
Authors : Rakhmankina V.A.; Tsareva O.A.;
Page : 23-28
Keywords : cells; rats; hypothyroidism; hypophysectomy;
The ultrastructure of the C-cells of the thyroid gland in hypophysectomyzed rats was studied. Morphometric studies of the nuclear apparatus and cytoplasm with organelles C-cells were held at the ultrastructural level. Nuclear-nucleolar ratio and the ratio of euchromatin and heterochromatin were studied in experiment. Area euchromatin increased in the nucleus. The amount of cristae in mitochondria and the average area of mitochondria were estimated to study the energy of C-cells and the energy efficiency ratio compartment was calculate on the basis of morphometric data. The number of mitochondria is increased in the cell. The number of cristae is increased in mitochondria. The energy efficiency ratio compartment increases. Degranulated form of C-cells predominant. The ultrastructural changes indicating C-cells hyperfunctional condition on the background of the thyroid hormone function were discovered.
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