TREATMENT OF INITIAL KERATOCONUS BY MEANS OF PATHOGENETICALLY DIRECTED CORNEAL COLLAGEN CROSSLINKING

The modern level of science development allows to expand considerably possibilities of various eye diseases diagnosis, in this connection the epidemiological situation of a number of corneal ecstasies is changed in the last decades. As changes of biomechanical properties of a human cornea play a significant role in emergence of a keratoconus, the corneal collagen crosslinking is the unique technique capable to strengthen a cornea. A considerable lack of a classical technique is the obligatory preliminary epithelial removal of a cornea for full saturation by Riboflavinum solution that inevitably involves the discomfort connected with a corneal syndrome and other possible complications in the postoperative period. The research purpose is the evaluation of efficiency and safety of collagen crosslinking of keratic collagen by intrastromal (intra corneal) injection of 0.1% of water solution of Riboflavin with Dextran that allows not only to avoid unpleasant consequences of deepithelialization, but also, indirectly increasing cornea thickness, to carry out the crosslinking on corneas less than 450 nanometers thicker.