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Fatal Stevens-Johnson syndrome induced by phenytoin: a case report

Journal: International Journal of Basic & Clinical Pharmacology (Vol.2, No. 6)

Publication Date:

Authors : ;

Page : 843-845

Keywords : TENS (Toxic Epidermal Necrolysis Syndrome); Phenytoin; Stevens-Johnson syndrome (SJS); Lyell syndrome;

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Abstract

Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are rare (one to two per 10,00,00 population per year) but life threatening adverse drug reactions. Drugs commonly implicated are anti-epileptics, anti-microbials and non-steroidal anti-inflammatory drugs (NSAIDS). Amongst anti-epileptics, carbamazepine and phenytoin are the major culprits. We report here a fatal case of SJS due to phenytoin. [Int J Basic Clin Pharmacol 2013; 2(6.000): 843-845]

Last modified: 2013-12-16 02:27:22