ANTIMICROBIAL SENSITIVITY PATTERN OF E.COLI IN URINARY TRACT INFECTION-A RETROSPECTIVE ANALYSIS

Aim- To determine the current trends in antibiotic susceptibility pattern of E. coli at a tertiary care hospital in, in- patients with urinary tract infections. Materials and methods- A retrospective analysis was done in Tirunelveli Medical College Hospital on 3581 urine culture reports issued for suspected urinary infections in, inpatients of the hospital during a 6months period. The common microorganisms causing urinary tract infections and microbial drug sensitivity pattern were analyzed on 578 samples which were found to be culture positive. Results- The common uropathogen identified was E.coli (38.2). The frequency of urinary infections in percentage was more in the age groups 0-9years (10.2) 50-59years (9.6) in males whereas in females it was more in the age group of 20-29(14.8). The aminoglycoside antibiotic amikacin showed the highest sensitivity (94.19) towards E.coli and cotrimoxazole s h o w e d t h e l e a s t s e n s i t i v i t y (15.9).Conclusion- E.coli is the predominant uropathogen identified in our hospital, showing the highest sensitivity to the amino glycoside, amikacin and the least sensitivity to cotrimoxazole