A case report of false positive Bence Jones proteinuria

With only rare exceptions,Bence-Jones proteinuria reflects a malignant condition. BJP occurs frequently in patients with Multiple myeloma. It is a plasma cell dyscrasia characterised by monoclonal proliferation of B cells. When there is excess production of antibodies light chains production exceeds heavy chain production and the excess light chains get excreted resulting in positive Bence Jones proteinuria. Monoclonal production of antibodies causes a discrete, intense band in the gamma region called as M band, the hallmark for the diagnosis of multiple myeloma. Though Bence Jones proteinuria is not a prerequisite for the diagnosis of multiple myeloma, positive bence jones proteinuria points towards the diagnosis of multiple myeloma. Here we report a false positive case of bence jones proteinuria normal Electrophoresis pattern.