Preparation and Characterization of Collagen:Amorphous Calcium Phosphate Composites

Collagen:amorphous calcium phosphate compositions were prepared by lyophylization and spongious composites for regeneration of bone defects were obtained. The spongious composites were characterized by Fourier transform infra-red (FT-IR) spectroscopy, scanning electron microscopy (SEM), water absorption and enzymatic degradation by collagenase. The results showed spongious composites with interconnected pores with embedded particles of mineral phase. Their biodegradation is less for the composite with 75% amorphous calcium phosphate (ACP3), as results of FT-IR and collagenase degradation showed. Due to their properties, the obtained composites could be potential biomaterials for bone tissue engineering.