ANATOMICAL AND HISTOPATHOLOGICAL EVALUATION OF LARGE INTESTINAL TUMORS

OBJECTIVE: To evaluate the anatomical and histopathological pattern of large intestinal tumors PATIENTS AND METHODS: This descriptive case series study of two years was conducted at Liaquat University Hospital Hyderabad. The inclusion criteria of the study were patients ≥12 years of age, either gender, diagnosed as large intestine malignancy were recruited and enrolled in the study. All surgically resected intestinal specimens were grossly observed and after kept in 10% formalin sent to laboratory for histopathological examination. The data was recorded on pre-designed proforma and analyzed in SPSS 16. The frequency, percentages and mean ±SD was computed for study variables. RESULTS: During two year study period, total 30 patients diagnosed as intestinal malignancy. The mean age ± SD for whole population was 58.75±6.51 with female gender predominance. The rectal malignancy was commonly observed 15 (40%) followed by transverse colon 3(10%). The adenocarcinoma was predominant 22 (73.3%) well differentiates 24 (80%) and ulcero-infiltrative 12 (40%) pattern. CONCLUSION: Tumors of the digestive tract show a wide variation in the anatomical and histological type, thus early evaluation is beneficial for appropriate management. Keywords: Intestinal tumors, Rectum carcinoma and Histopathology.