Serum uric acid level is not associated with severity and extent of coronary disease in patients with acute coronary syndromes - Our experience

Background: We evaluated Correlation of Serum Uric Acid level in patients with acute coronary syndromes with severity and extent of coronary disease Materials and methods: Fifty-one patients with acute coronary syndromes between 25-60 years were included into the study. Patients with chronic kidney disease, gout, hematological malignancy, hypothyroidism, chronic alcoholism, receiving diuretic therapy, more than 2 grams per day of salicylate therapy, ethambutol, pyrazinamide, were excluded. Data regarding history, ECG, cardiac enzymes, serum uric acid, and angiographic details were recorded. Results: The mean age of the study population was in 55.68± 5.83 years. The age, gender BMI, and co morbidities such as smoking, obesity, diabetes, hypertension and family history were not statistically significant across types of ACS, such as CSA, USA and MI. We noticed that uric acid levels were not significantly (P>0.05) across types of ACS. We also found significant correlations between uric acid levels at admission with age, hypertension and family history. However, there was no significant correlation of uric acid with the type of a number of vessels involved and Killip classification. Conclusion: In the current study, serum UA level in patients with acute coronary syndromes is not associated with Killip class and extent of coronary vessels involved.