Is antibacterial PNA the answer for combating multidrug resistant bacterial infections?
Journal: International Journal of Biosciences (IJB) (Vol.10, No. 1)Publication Date: 2017-01-15
Authors : Anubrata Ghosa;
Page : 408-410
Keywords : PNA; drug resistance bacteria; antibiotics.;
Abstract
The emergence of multidrug resistant bacterial infections is a serious problem. Treatment options are limited to patients those are infected with multidrug resistant bacteria. We are in a desperate need of new antibiotics. Antisense oligomers of PNA (Peptide Nucleic Acid) were introduced in late 90's as antibacterial agents in an intention to create a new class of bacterial specific antibiotic. Followed by several studies have demonstrated that antibacterial PNA oligomers are effective in a verity of pathogenic bacterial strains. Development of PNA-based drugs (PNA antibiotics) will help us to combat infections of drug resistant bacterial strains.
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