Interleukin-1 beta response to an acute incremental cycling in obese men

To compare of circulating levels of IL-1b as an inflammation cytokine between obese and none obese men and also to investigation its response to an acute exercise test. Fasting blood samples were obtained of adult obese (n=15) and none obese (n=14) men aged 40 ± 5 year in order to measuring serum IL-1b and glucose. In addition, blood samples were repeated immediately after a session cycling exercise in order to determine these variables responses to exercise test. Statistic analysis was done with SPSS 15.0 for Windows by using Student's t-tests for independent and paired samples. At baseline, serum IL-1b level, glucose and insulin resistance in obese men were higher than those with normal weight (p < 0.05). Acute cycling test increased IL-1b (p = 0.037) and decreased glucose concentration (p = 0.024) without changes in insulin resistance (p = 0.126) on obese subjects. Obesity is associated with systemic inflammation. Despite the decrease in glucose concentration, but a session exercise does not lead to improved systemic inflammation in obese men.