Evaluation of anti-inflammatory and antipyretic activity of oldenlandia umbellata linn roots

The ethanolic extract of Oldenlandia umbellata (synonym: Hedyotis umbellata) root was screened for both anti-inflammatory and antipyretic activity in wistar albino rats. The extract showed significant anti-inflammatory activity in carrageenan induced paw oedema, which is comparable to that of the control and standard drug phenylbutazone. Antipyretic activity screened by brewer’s yeast induced pyrexia in albino rats. It is comparable to that of paracetamol. The results indicated that Oldenlandia umbellata root is endowed with potential anti-inflammatory and antipyretic activity.