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Melioidosis Mimicking Tuberculosis in an Endemic Zone: A Case Report

Journal: Bangladesh Journal of Infectious Diseases (Vol.2, No. 1)

Publication Date:

Authors : ; ; ; ; ; ; ; ; ; ;

Page : 23-26

Keywords : Melioidosis; tuberculosis; Burkholderia pseudomallei;

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Abstract

Melioidosis is not widely recognized in Bangladesh which is evident from the paucity of published reports on melioidosis from this region. Here, we summarize the clinical presentation, laboratory results, prevention, and control policies and make important recommendations for patient management. A 35-years-old diabetic male forest officer from Gazipur Sadar located northwest of Dhaka city got admitted to Shaheed Suhrawardy Medical College Hospital, Dhaka with a history of recurrent fever for last 1 year. Initially, the fever was high grade (up to 1050F), intermittent nature and lasted for a few days to a week. About five months back, the patient developed a parietal abscess over the left lumbar region and was treated surgically accordingly. The patient then gradually recovered and remained afebrile for about one month. Fever again recurred, high grade, quotidian in nature and has been persistent for the last 3 months. The patient had also developed marked loss of appetite, altered bowel habit with occasional vomiting and lost about 15kg of his body weight. The patient noticed profuse watery diarrhea for last 2 days and got himself admitted. On examination, the patient was found wasted, conscious but slow mentation, dehydrated and moderately anemic. His pulse was 116/min, blood pressure 80/60 mm Hg, respiration 24/min, and the oral temperature were 1030F but no palpable lymph nodes. The patient had moderate hepatosplenomegaly with left-sided pleural effusion and bilateral depressed ankle jerks. Burkholderia pseudo mallei were isolated and identified by blood and urine culture as well as with serological test. We should be more alert among the diabetic patients who are presented with fever with high ESR and neutrophilic leucocytosis, even if radiography or cytopathology is indicative of tuberculosis.

Last modified: 2017-05-13 15:54:53