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Brown Tumors or Bone Metastases in Context of Parathyroid Carcinoma: A Diagnostic Challenge

Journal: International Journal of Bone and Rheumatology Research (IJBRR) (Vol.03, No. 05)

Publication Date:

Authors : ; ; ; ;

Page : 46-49

Keywords : Hyperparathyroidism; Brown Tumor; Parathyroid Carcinoma; Positron Emission Tomography/Computed Tomography; Parathyroidectomy;

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Parathyroid carcinoma is a rare cause of primary hyperparathyroidism. When this malignancy is diagnosed, often there are distant metastases (usually liver and/or bone). Brown tumor is a localized form of osteitis fibrosa cystica; classic manifestation in bone of excess parathyroid hormone and this is a bening pathology. We encountered an unusual case of parathyroid carcinoma with images that mimicked metastatic bone tumors, whose differential diagnosis with brown tumor may be complicated. Positron emission tomography/computed tomography (PET/CT) scan was requested for the evaluation of fluorodeoxyglucosa uptake of these lesions. PET/CT images showed multiple hypermetabolic images that mimicked multiple skeletal metastasis but brown tumors could not be dismissed.

Last modified: 2017-05-31 14:29:23