Study the Effect of Dexmedetomidine on Emergence Agitation after Nasal Surgeries

Background: Emergence agitation is a short lived phenomenon occurring commonly after nasal surgery. In this study we used dexmedetomidine infusion in that intraoperative period to decrease the incidence of emergence agitation in adult male and female patients posted for nasal surgery. Aim: Study the effect of dexmedetomidine on emergence agitation after nasal surgeries. Materials and methods: 110 adult patients (ASA I-II, 22-65 years posted for nasal surgery were randomly divided into two groups. Group D received infusion of dexmedetomidine 0.4mcg/kf/hr during the intraoperative period, and Group C received normal saline infusion as placebo. All patients were induced with fentanyl (1 mcg/kg) and propofol (1.5 mcg/kg) and maintained with isoflurane. Incidence of agitation, hemodynamics, pain scores, time to verbal commands and extubation were evaluated. Results: Incidence of emergence agitation was lower in Group D (26%) than Group C (50%). Group I showed more stable hemodynamics than Group II. Time to verbal response and extubation was more for Group D than Group C (p < 0.05) though it was not clinically significant. Conclusion: The use of dexmedetomidine as intraoperative infusion resulted in smooth emergence with more stable hemodynamics.