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Metformin and Kidneys - A Contentious Relationship
Journal: Austin Journal of Nephrology and Hypertension (Vol.1, No. 3)Publication Date: 2014-08-22
Authors : Metformin; Chronic kidney disease; Lactic Acidosis;
Page : 1-4
Keywords : ;
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Abstract
Metformin has evolved as the most popular anti-diabetic medicine worldwide. Way back in 1998 United Kingdom Prospective Diabetes Study (UKPDS) Group had shown that it is the only oral hypoglycemic agent that has proven to reduce cardiovascular mortality in diabetes mellitus type 2 (DM2). Various reports have shown its safety but amongst many practitioners, there is still fear of lactic acidosis (LA). This concern is further heightened in diabetic patients with chronic kidney disease (CKD). Here we review if that is still a valid concern or not.
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Last modified: 2017-06-12 17:57:57