ESBL-Producing E. Coli in a Patient on Automated Peritoneal Dialysis

Peritoneal Dialysis (PD) is one of the 3 well-established modalities of renal replacement therapy used in patients with renal failure. Despite its significant role as a successful method of renal replacement therapy, PD is highly associated with peritonitis and catheter-related infections. ESBL-producing E. coli (ESBL-EC) is uncommonly isolated in the peritoneal dialysate and are resistant to the currently recommended empiric antibiotics for peritoneal dialysis peritonitis (PDP). The optimal treatment of ESBL-EC cultured in the peritoneal dialysate is still lacking. Here, we report a case of 68 years old female on automated peritoneal dialysis, who presented with symptoms of peritonitis, with a peritoneal dialysate culture positive for ESBL-EC.