Extramedullary Plasmacytoma of the Nasal Cavity: Case Report

The extramedullary plasmacytoma is a rare malignant proliferation clone secreting a monoclonal immunoglobulin. The location to the upper aerodigestive tract represents 80-90% of cases. We report a extramedullary plasmacytoma nasopharyngeal location in a 39 year old patient. She consulted for nasal obstruction and recurrent epistaxis. The endoscopic exploration and CT scan of the nasal cavities revealed a tumor process of the posterior superior wall of nasopharynx. Histological study of biopsy confirmed the location of a nasopharyngeal plasmacytoma to light chains Kappa with amyloid deposits. A comprehensive review of possible multiple myeloma was negative and finding an isolated extramedullary plasmacytoma. The patient received chemotherapy and radiotherapy with favorable evolution.