Synthesis, physiochemical studies, anti-inflammatory and analgesic activities of some metal complexes of Zr (IV) with amino acidsJournal: International Journal of Engineering and Technical Research (www.erpublication.org) (Vol.1, No. 8)
Publication Date: 2013-10-30
Authors : Anwar Hossain; Chanmiya Sheikh; SK AL Zaheri Mahmud; Ronok Zahan; Ashraful Alam;
Page : 44-48
Keywords : erpublication; IJETR;
New zirconium(IV) complexes were synthesized with 4,4'-bipyridine, imides and some amino acids in the solid form and characterized by elemental analysis, conductivity, magnetic moment measurement, FT- IR, 1H-NMR, 13C-NMR and FAB+ mass studies. For studying anti- inflammatory and analgesic activities of theses complexes some Swiss albino mice of 6-7 weeks old were taken. The test compounds of 20 mg/kg for each were selected throughout the research work. The antiinflammatory activity of the test compounds was determined by ‘carragenan induced mice paw edema inhibition' method. The analgesic activity was determined by ‘acetic acid induced writhing' methods. These three compounds have showed positive effects as anti-inflammatory and analgesic agents.
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