A study of injectable aceclofenac for acute postoperative pain in laparoscopic abdominal surgeries

Background and Objectives: Postoperative pain management is always a challenging task even though many modalities have been studied. The present study would like to compare the effects of two Nonsteroidal anti-inflammatory agents by Intramuscular route. The present study is undertaken to evaluate and compare the efficacy and duration of action of intramuscular injectable aceclofenac 150mg/3ml with intramuscular injectable diclofenac 75mg/3ml. Material and Methods: The present study was undertaken compare the relative efficacy of aceclofenac and diclofenac by intramuscular route for postoperative analgesia in patients undergoing laparoscopic abdominal surgeries. A randomized study was conducted on 50 patients, planned for laparoscopic abdominal surgeries under general anaesthesia. In two groups containing 25 patients each the group A received injection (Inj) aceclofenac intramuscularly and group B received injection diclofenac intramuscularly. Perioperative haemodynamics were assessed and monitored. Postoperatively visual analogue score, pulse rate and mean arterial pressure were recorded at 2, 4, 6, 8, 12 and 24 hours duration intervals. Results: Both aceclofenac and diclofenac are efficient for providing postoperative analgesia in patients undergoing elective laparoscopic abdominal surgeries. Both the groups exhibited haemodynamic stability. Incidence of rise in pulse rate and MAP in the postoperative period was higher with inj. diclofenac than inj. aceclofenac. Inj. aceclofenac in our study scores over inj. diclofenac in providing better quality of analgesia.