SERUM ADENOSINE DEAMINASE LEVEL IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Objective: to evaluate the serum adenosine deaminase level in patients with type 2 diabetes mellitus at tertiary care hospital Hyderabad. Patients and Methods: This six month cross sectional descriptive study was conducted in the department of medicine at tertiary care hospital Hyderabad. The inclusion criteria of this cross sectional study (six months duration) were the individuals with uncomplicated type 2 diabetes mellitus had ≥35 years of age and both male and female gender. The study diabetic population was screened for serum adenosine deaminase level by taking 2 cc venous blood sample and sent to laboratory for analysis. The frequency and percentages was calculated while the mean ±SD was computed for numerical variables. Results: Total fifty type 2 diabetic individuals were studied during six months study period, the mean age ± SD for whole population was 52.87±8.85 while mean ±SD for fasting and random blood glucose and HBA1C was 131.21±4.82 and 230.63±9.94 and 10.72±2.43 respectively. The male population was predominant 35 (70%) while the serum ADA was raised in 29 (58%) type 2 diabetic populations and also correlates with HBA1C 23 (79.3%) Conclusion: serum ADA levels play an important role in evaluating the glycemic status and an indicator in the immuno-pathogenesis of diabetes mellitus. Keywords: Diabetes mellitus, adenosine deaminase and Metabolism