WOUND HEALING ACTIVITY OF TRIPHALA IN EXPERIMENTALLY INDUCED DIABETIC RATS

Aim of the present study was to explore the wound healing potential of Triphala extract. Triphala ointment (15% w/w) was used in the study for excision wound model. For dead space wound model Triphala extract (200 mg/kg) was administered orally. Extract of Triphala topically applied in excision wound model was found to possess wound healing property. On day 11th, the extract treated animals showed wound contraction to the extent of 87.63% and 94.77%, compared with control group of animals. In dead space wound model, oral administration of the extract was found to increase the wet and dry granuloma weight of tissue. The extract treated animals showed high quantity of hydroxyproline content when compared with the control group animals. The topical and oral administration of Triphala extract promotes diabetic wound healing in streptozotocin induced diabetic rats with increased rate of wound contraction and collagen turnover.