STUDY ON PHARMACOGNOSTICAL AND ANTIBACTERIAL ACTIVITY OF ZIZIPHUS XYLOPYRUS

The present study focuses on, screening the anti-bacterial activities of methanol and chloroform extracts of the dried stem barks of Ziziphus xylopyrus. The anti-bacterial activities were evaluated against fifteen different bacterial strains by detecting minimum inhibitory concentration and zone of inhibition. The minimum inhibitory concentration (MIC) values were compared with control and zones of inhibition (ZOI) were compared with standard ciprofloxacin at concentration of 100 and 200 μg/mL. Among the two extracts, the methanolic extract showed better antibacterial activity compared to chloroform extract . The MIC values for different bacterial strains obtained were within the range of 100-300 μg/mL. The ZOI values showed that there was a little differences in the ZOI values between the standard and methanol extract within the range of 0.5 to 1mm. This was comparable with the standard drug. Anatomical, proximate analysis and chromatographic studies were also carried out to fulfill the botanical quality control standards.