Leptin in non PCOS and PCOS women: a comparative study

Background: Leptin, a hormone secreted by adipose tissues, controls body weight through regulation of appetite and thermogenesis. The present study was aimed to observe role of leptin in healthy and polycystic ovary syndrome (PCOS) women. Methods: Correlation between serum leptin and anthropometric, endocrine and metabolic profile was studied in 30 apparently healthy women (control group) and 38 PCOS women (PCOS group). Each group was stratified based on body mass Index (BMI), as normal weight (BMI23). Results Leptin level was high in 30% control group and in 65.79% PCOS group. Mean leptin (ng/ml) in PCOS group was higher compared to control group.