EXTRACORPOREAL BLOOD PURIFICATION IN SEPSIS: MODERN STATE OF THE PROBLEM

Current approaches to the use of methods of extracorporeal blood purifiation in the intensive therapy of sepsis are under analysis in this literature review. The most common methods such as haemoperfusion, plasmapheresis, continuous venovenous haemofitration and haemodiafitration, extracorporeal liver support have been analyzed. In terms of the evidence-based medicine the extracorporeal blood purifiation procedure has been demonstrated to be an effective method in the treatment of septic patients of various profies and degrees of disease severity. The evidencebased methodology of the integrated treatment of patients with sepsis comprises continuous methods of the renal replacement therapy as well as haemoperfusion through selective hemosorbents. The use of extracorporeal blood purifiation in sepsis reduces the death rate in patients with various degree of severity of the initial state.