AN INTERESTING CASE OF MYCOSIS FUNGOIDES

Abstract : Mycosis fungoides is the most common of the primary cutaneous T cell lymphomas . We descibe a 58 year old male who presented with features of plaque stage of Mycosis fungoides. The lesions initially started around the hip as hyperpigmented plaques which was followed by similar lesions over legs, trunk, arms and other regions of the body gradually in 10 yrs. History of loss of weight and appetite was present . Dermatological examination revealed multiple well-defined hyperpigmented thickened scaly plaques of varying sizes present over trunk, face and extremities. Right axillary lymphnodes were enlarged, firm, discrete and nontender. Immunohistochemistry showed CD 3 and CD 4 positivity and histopathological examination was consistent with Mycosis fungoides. The patient was treated with 6 cycles of Total Skin Electron Beam Radiotherapy, followed which he showed dramatic improvement in skin lesions . We report this case for its rareity and interesting presentation . Keyword :Immunohistochemistry, Epidermotropism, Mycosis fungoides, Total Skin Electron Beam Radiotherapy.