STAGE 4 RETINOBLASTOMA IN A 13 YEAR OLD GIRL A CASE REPORT

Introduction-Retinoblastoma is rare after 3 years of age, the mean age of diagnosis being18 months in bilateral retinoblastoma and 24 months in unilateral cases. We report a 13 year old girl with unilateral retinoblastoma and intracranial extension. Case History- The girl presented with loss of vision in the left eye and prominence of the left eye along with pain for 2 months duration. Clinical examination of the left eye revealed no perception of light, proptosis, shallow anterior chamber, neovascular glaucoma and total cataract. A review of imaging done 10 months prior to presentation showed a heterogenous intraocular mass partially filling the globe with no optic nerve involvement. Amore recent Imaging showed the tumour completely filling the globe with optic nerve involvementupto the chiasm. The differential diagnoses included optic nerve glioma and meningioma withintraocular involvement, retinoblastoma with intracranial extension and an intraocular inflammation with extension. The eye was enucleated and histopathological examination showed malignant round cell tumour consistent with retinoblastoma. Conclusion-The differential diagnoses and relevant literature review of an intraocular tumour with intracranial involvement is discussed. Although rare, retinoblastoma should be considered as a differential diagnosis for an intraocular tumour with wide spread involvement in a teenager.