DENDRITIC CELL VACCINATION AS POST-REMISSION TREATMENT TO PREVENT OR DELAY RELAPSE IN ACUTE MYELOID LEUKEMIA
Journal: Synergy of Science (Vol.14, No. 1)Publication Date: 2017-08-31
Authors : Chkhaabra I.R.; Kharchenko S.V.;
Page : 0-0
Keywords : acute myeloid leukemia; dendritic cell vaccination; blast cells; hematopoietic pathologies; relapses in leukemia; myeloblasts.;
Abstract
It is known that leukemia is a disease of the bone marrow, respectively, in this disease there is a violation of normal hematopoiesis (usually the formation of blast cells - precursors of leukocytes, which subsequently interfere with the development and functioning of normal leukocytes) Acute myeloid leukemia to date (the pathology of the development of myeloid cells, myeloblasts, etc.) is a rare pathology in children (about 14% of cases), which, unfortunately, it can not be said about patients which are 40-45 years old and older - because in this age period there is a sharp increase in the incidence. There is no single cause of acute myeloid leukemia to date. According to scientists, this disease can be a consequence of prolonged exposure to ionizing radiation on the body, a number of chemicals, and may also result from a genetic predisposition. Relapse is a major problem in acute myeloid leukemia and adversely impacts survival.
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Last modified: 2017-08-27 19:38:50