Etanercept as Rescue Therapy for Refractory Kawasaki Disease

Kawasaki disease is a febrile vasculitis occurring in infants and children treated with first line intravenous immunoglobulin (IVIG) and aspirin. However unresponsiveness to IVIG is not rare. This case report illustrates a girl with Kawasaki disease with fever persisting through two doses of IVIG and methylprednisolone and her fever was subsided only after using etanercept, a tumor necrosis factor-α antagonist.